HIV prophylaxis expensive and sometimes difficult to obtain

Why scaffolding should sometimes make tasks more difficult for learners

ABSTRACT There has been much interest in using software tools to scaffold learners in complex tasks, that is, to provide supports that enable students to deal with more complex content and skill demands than they could otherwise handle. Many different approaches to scaffolding techniques have been presented in a broad range of software tools. We discuss two mechanisms to explain how software to...

Peristomal Skin Complications Are Common, Expensive, and Difficult to Manage: A Population Based Cost Modeling Study

BACKGROUND Peristomal skin complications (PSCs) are the most common post-operative complications following creation of a stoma. Living with a stoma is a challenge, not only for the patient and their carers, but also for society as a whole. Due to methodological problems of PSC assessment, the associated health-economic burden of medium to longterm complications has been poorly described. AIM ...

Biological Aspects and Clinical Applications of Nanoparticles on Treatment and Prophylaxis of HIV

Acquired Immune Deficiency Syndrome (AIDS) is a descriptive type of immune system dysfunction disorder which is caused by HIV infection. Since its discovery, HIV has been responsible for the death of more than 25 million people worldwide, and many people are infected with HIV each year. Because of the structural complexity of the virus and the lack of a promising vaccine, several antiviral drug...

Prevention of Iodine Deficiency: Difficult to Implement, More Difficult to Sustain

Streamlining HIV testing for HIV preexposure prophylaxis.

HIV-testing algorithms for preexposure prophylaxis (PrEP) should be optimized to minimize the risk of drug resistance, the time off PrEP required to evaluate false-positive screening results, and costs and to expedite the start of therapy for those confirmed to be infected. HIV rapid tests (RTs) for anti-HIV antibodies provide results in less than 1 h and can be conducted by nonlicensed staff a...